Tyler Bishop | Voluntary Public Medical Records

Updated labs and tests for Tyler open sourced (with most records included from the past 8 years)

Name
Tyler Bishop
DOB
05/26/1987
Age
38 years
Sex
Male
Location
San Diego, CA
Records Span
2017-2026
PUBLIC On Purpose
📄 View Lab Reports
Key Health Metrics (Latest: 02/24/2026)
Factor VIII Activity
147%
Reference: 56-140% — HIGH
vWF Antigen
143%
Reference: 50-200%
vWF Activity
126%
Reference: 50-200%
Uric Acid
5.6
Reference: 3.8-8.4 mg/dL
Glucose
78
Reference: 70-99 mg/dL
Creatinine / eGFR
0.95 / 105
Ref: 0.76-1.27 / >59
AST / ALT
26 / 25
Reference: 0-40 / 0-44 IU/L
ESR / CRP
2 / <1
No inflammation detected
D-Dimer
0.37
Reference: <0.50 ug/mL FEU
Tryptase
5.9
Reference: 2.2-13.2 ug/L
24hr Urine Creatinine
1861
Reference: 1000-2000 mg/24hr
Liver (US 02/17)
Fatty
Increased echogenicity on imaging
Recent Notable Findings
Test Latest Result Reference Range Status Notes
Creatinine / eGFR 0.95 mg/dL / 105 0.76-1.27 / >59 Excellent Best kidney function values in years (Jan 16, 2026)
LDH Total 232 IU/L 121-224 HIGH Slightly elevated (Jan 16 & 19, 2026); LD fractions show normal distribution
AST / ALT 26 / 25 IU/L 0-40 / 0-44 Normal Excellent — Major improvement from 62/95 in Nov 2024
ESR / CRP 2 mm/hr / <1 mg/L 0-15 / 0-10 Normal No systemic inflammation (Jan 16, 2026)
Tryptase 5.9 ug/L 2.2-13.2 Normal Stable from 6.0 (Jan 12); rules out mast cell disorders
Urine pH 8.0 5.0-7.5 HIGH Alkaline urine, likely due to good hydration (Jan 16, 2026)
Creatinine, 24hr Urine 1861 mg/24 hr 1000-2000 Normal Normal renal creatinine clearance confirmed (Jan 16, 2026)
Abdominal Ultrasound Fatty Liver ABNORMAL Increased hepatic echogenicity (fatty infiltration); GB polyp 3 mm (Feb 17, 2026)
Factor VIII Activity 147% 56-140% HIGH Elevated on vWF panel (Feb 24, 2026); associated with increased VTE risk
vWF Antigen / Activity 143% / 126% 50-200% Normal Rules out von Willebrand Disease (Feb 24, 2026)
Uric Acid 5.6 mg/dL 3.8-8.4 Normal Rules out gout/hyperuricemia as cause of joint inflammation (Feb 24, 2026)
LD Isoenzymes / LDH Fractions (01/16/2026 & 01/19/2026) ⚠️

LDH was elevated on both test dates. Isoenzyme fractionation (01/19/2026) measures the different "fractions" of Lactate Dehydrogenase to pinpoint tissue damage.

Test Result Reference Interval Status
LDH Total (01/16/2026) 232 IU/L 121–224 IU/L HIGH
LDH Total (01/19/2026) 231 IU/L 121–224 IU/L HIGH
LD Fraction 1 (Heart, RBC) 31% 17–32% Normal
LD Fraction 2 (Heart, RBC) 34% 25–40% Normal
LD Fraction 3 (Lung, Lymph) 20% 17–27% Normal
LD Fraction 4 (Liver, Muscle) 8% 5–13% Normal
LD Fraction 5 (Liver, Muscle) 7% 4–20% Normal
Analysis: While total LDH is slightly elevated at 231 IU/L, all individual LD fractions are within normal limits. The normal LD1/LD2 ratio rules out acute myocardial infarction or hemolysis as causes. Normal LD4/LD5 suggests no active liver or muscle damage. The mild LDH elevation may be due to minor cellular turnover or sample handling. Continue monitoring.
⚠️ Critical Finding: Synovial Fluid Analysis (01/04/2026)

Source: Right Elbow — This report indicates hemarthrosis (bleeding into the joint), which is a significant finding.

Test Result Reference Status
Appearance Bloody Clear ABNORMAL
Color Red Yellow ABNORMAL
RBC Count 3,197,000 /mcL < 2,000 /mcL CRITICAL HIGH
Nucleated Cells 2,570 /mcL 0–200 /mcL HIGH
Neutrophils 68% < 25% HIGH
⚠️ Clinical Significance: The synovial fluid analysis reveals hemarthrosis with extremely elevated RBC count (3.2 million vs normal <2,000). Elevated nucleated cells and neutrophils suggest an inflammatory response to the blood in the joint space.

Follow-up testing (01/16/2026): Factor V Leiden negative, Antiphospholipid panel (all 6 antibodies) negative, C1 Esterase Inhibitor (serum & functional) normal, Tryptase normal. ESR 2, CRP <1 — no systemic inflammation.

Follow-up testing (02/24/2026): Comprehensive coagulation panel normal (Factor VIII 137%, Factor IX 91%, Factor XI 90%, Fibrinogen 226, APTT 28.2, PT 10.8, INR 1.0, D-Dimer 0.37). Von Willebrand Disease ruled out (vWF Antigen 143%, vWF Activity 126% — both normal). Antiphospholipid antibodies negative on repeat testing (second confirmation). Uric acid 5.6 mg/dL — normal, rules out gout/crystal arthropathy. ⚠️ Notable: Factor VIII elevated at 147% (ref 56–140) on vWF panel.

Status: Cause of hemarthrosis remains undetermined despite extensive workup. All inherited coagulopathies tested negative. No autoimmune or crystal-driven etiology identified. Elevated Factor VIII is an acute-phase reactant and may be reactive rather than causative. May warrant continued hematology follow-up.
Complete Blood Count (CBC) - Historical Data
Test Date WBC (x10E3/uL) RBC (x10E6/uL) Hemoglobin (g/dL) Hematocrit (%) MCV (fL) MCH (pg) Platelets (x10E3/uL)
12/18/2017 5.1 4.60 13.8 40.0 87 30.0 247
08/28/2018 4.7 4.41 13.4 38.4 87 30.4 222
11/18/2024 4.8 4.46 13.5 40.2 90 30.3 288
07/17/2025 5.0 4.64 14.1 42.7 92 30.4 272
01/16/2026 5.6 4.70 13.7 41.6 89 29.1 324
Notes: All CBC values remain within normal reference ranges. Most recent values (01/16/2026) show stable WBC, RBC, hemoglobin and hematocrit. Platelet count increased to 324 but remains well within normal range (150-450). WBC slightly increased from 5.0 to 5.6 but still normal.
Comprehensive Metabolic Panel (CMP) - Historical Data
Test Date Glucose (mg/dL) BUN (mg/dL) Creatinine (mg/dL) eGFR Sodium (mmol/L) Potassium (mmol/L) Chloride (mmol/L) Calcium (mg/dL)
12/18/2017 90 10 1.00 101 - - - -
08/28/2018 86 10 1.06 93 141 4.3 100 9.9
02/07/2020 92 7 1.02 97 140 5.1 99 9.9
11/18/2024 90 16 1.14 85 139 4.4 99 9.9
07/17/2025 87 17 1.14 84 139 5.3 101 10.1
01/16/2026 78 13 0.95 105 140 4.5 98 10.2
Trends & Notes: Glucose levels stable and normal (77-92 mg/dL). Creatinine improved to 0.95 in Jan 2026 (lowest in years). eGFR excellent at 105 mL/min/1.73, indicating strong kidney function. 24-hour urine creatinine (1861 mg/24 hr, ref 1000-2000) confirms normal renal clearance. BUN normalized to 13. Potassium improved from borderline-high 5.3 (Jul 2025) to normal 4.5. All electrolytes (Na, K, Cl, Ca) within normal ranges.
Liver Function Panel - Historical Data
Test Date AST (IU/L) ALT (IU/L) ALP (IU/L) Bilirubin (mg/dL) Albumin (g/dL) Total Protein (g/dL)
08/28/2018 37 24 52 1.5* 4.9 6.8
02/07/2020 - - - - 4.7 -
11/18/2024 62* 95* 79 1.1 4.7 6.6
07/17/2025 31 30 77 1.0 4.6 6.6
01/16/2026 26 25 89 1.1 4.9 6.9
Additional Liver Markers (01/16/2026)
GGT (Gamma-Glutamyl Transferase)
15 IU/L
Reference: 0-65 IU/L
LDH (Lactate Dehydrogenase)
232 IU/L
Reference: 121-224 IU/L (Slightly elevated)
Abdominal Ultrasound (02/17/2026)
Liver Echogenicity
Increased
Fatty infiltration / hepatocellular disease
Liver Size
16.0 cm
No mass detected
Gallbladder Polyp
3 mm
Tiny; below threshold (<10 mm)
Portal Vein
Normal
10 mm, patent, antegrade flow
Trends & Notes: *Alert: AST and ALT were significantly elevated in Nov 2024 (62 and 95 IU/L respectively), but improved dramatically by July 2025. Current values (AST 26, ALT 25) are excellent and well within normal limits. GGT is normal at 15 IU/L. LDH slightly elevated at 232 (ref 121-224) — see LDH Isoenzymes section for detailed analysis. Total bilirubin normalized. Albumin (4.9) and total protein (6.9) excellent, indicating strong liver synthetic function. *Imaging (02/17/2026): Abdominal ultrasound reveals diffusely increased hepatic parenchymal echogenicity, typical of fatty infiltration (NAFLD/MASLD). Despite normalized liver enzymes, the imaging finding suggests underlying hepatic steatosis. Tiny gallbladder polyp (3 mm) noted — benign, monitor on follow-up. All other abdominal organs normal.
C1 Esterase & Tryptase Testing (01/12/2026 & 01/16/2026)

These tests evaluate for angioedema or mast cell activation disorders. Follow-up testing on 01/16/2026 confirms stable values.

Test 01/12/2026 01/16/2026 Reference Interval Status
C1 Esterase Inhibitor, Serum 29 mg/dL 26 mg/dL 21–39 mg/dL Normal
C1 Esterase Inhibitor, Functional 82 %mean normal >67 (Normal) Normal
Complement C1q, Quantitative 12.6 mg/dL 14.5 mg/dL 10.2–20.3 mg/dL Normal
Tryptase 6.0 ug/L 5.9 ug/L 2.2–13.2 ug/L Normal
Interpretation: All values within normal limits on both test dates. C1 Esterase Inhibitor Functional test (82%) confirms adequate enzyme activity, definitively ruling out hereditary angioedema (HAE) Types I and II. Normal serum C1 Inhibitor levels (26-29 mg/dL) are stable. Normal Tryptase levels (5.9-6.0 ug/L) rule out systemic mastocytosis and mast cell activation disorder. Complement C1q slightly increased from 12.6 to 14.5 but remains well within normal range.
Immune, Autoimmune & Infectious Disease Screening (11/18/2024)
Test Result Reference Range Status
HBsAg (Hepatitis B Surface Antigen) Negative Negative Normal
HCV Ab (Hepatitis C Antibody) Non Reactive Non Reactive Normal
Hepatitis B Core Ab, Total Negative Negative Normal
Hepatitis B Surf Ab Quant 34415.0 mIU/mL >10 (Immunity) Immune
QuantiFERON-TB Gold Plus Negative Negative Normal
Rheumatoid Factor (RF) <10.0 IU/mL <14.0 Negative
Anti-CCP Antibody <20 Units <20 Negative
Antinuclear Antibody (ANA) Negative Negative Negative
Sjogren's Anti-SS-A <0.2 AI 0.0-0.9 Negative
Sjogren's Anti-SS-B <0.2 AI 0.0-0.9 Negative
Smith Antibodies <0.2 AI 0.0-0.9 Negative
Anti-dsDNA Antibodies <1 IU/mL 0-9 (Negative <5) Negative
Anti-U1 RNP Antibody <20 Units <20 Negative
Anti-DFS70 Antibody <20 Units <20 Negative
HLA-B27 Negative Negative Negative
Complement C3, Serum 93 mg/dL 82-167 Normal
Complement C4, Serum 15 mg/dL 12-38 Normal
Celiac Disease (tTG IgA) <2 U/mL 0-3 Negative
Summary: All infectious disease screening tests (Hepatitis B, C, TB) negative or show immunity to Hepatitis B. All autoimmune markers (ANA, Rheumatoid Factor, Anti-CCP, connective tissue disease antibodies) are negative, effectively ruling out systemic autoimmune conditions. No evidence of celiac disease.
Inflammatory Markers (01/16/2026)

These markers help evaluate systemic inflammation and infection.

Erythrocyte Sedimentation Rate (ESR)
2 mm/hr
Reference: 0-15 mm/hr
C-Reactive Protein (CRP), Quantitative
<1 mg/L
Reference: 0-10 mg/L
Interpretation: Both inflammatory markers are excellent. ESR of 2 mm/hr and CRP <1 mg/L indicate no significant systemic inflammation. This is reassuring given the recent hemarthrosis finding — it suggests the joint bleeding is not associated with a systemic inflammatory process or active infection.
Urinalysis (01/16/2026)
Test Result Reference Status
Specific Gravity <1.005 1.005-1.030 LOW
pH 8.0 5.0-7.5 HIGH
Color Yellow Yellow Normal
Appearance Clear Clear Normal
WBC Esterase Negative Negative Normal
Protein Negative Negative/Trace Normal
Glucose Negative Negative Normal
Ketones Negative Negative Normal
Occult Blood Negative Negative Normal
Bilirubin Negative Negative Normal
Urobilinogen 0.2 mg/dL 0.2-1.0 mg/dL Normal
Nitrite Negative Negative Normal
Interpretation: Urinalysis is largely unremarkable. The low specific gravity (<1.005) and alkaline pH (8.0) suggest the patient was well-hydrated at the time of collection, which can dilute urine and raise pH. All other markers negative — no evidence of urinary tract infection (negative WBC esterase, nitrite), no proteinuria, no glucosuria, and no blood in urine. No microscopic examination was required.
Allergen-Specific IgE Testing (All Dates)
Total IgE
9 IU/mL
Reference: 0-100 IU/mL | Date: 08/28/2018
Allergen Classes (Class 0 = Negative <0.10 kU/L)

Environmental Allergens

Dust Mites (D. pteronyssinus)
Class 0 (Negative) - <0.10 kU/L
Dust Mites (D. farinae)
Class 0 (Negative) - <0.10 kU/L
Cat Dander
Class 0 (Negative) - <0.10 kU/L
Dog Dander
Class 0 (Negative) - <0.10 kU/L
Cockroach (German)
Class 0 (Negative) - <0.10 kU/L
Cockroach (American)
Class 0 (Negative) - <0.10 kU/L

Grass Allergens

Bermuda Grass
Class 0 (Negative) - <0.10 kU/L
Timothy Grass
Class 0 (Negative) - <0.10 kU/L
Johnson Grass
Class 0 (Negative) - <0.10 kU/L
Rye Grass (Perennial)
Class 0 (Negative) - <0.10 kU/L
Bahia Grass
Class 0 (Negative) - <0.10 kU/L

Tree Allergens

Alder (Grey)
Class 0 (Negative) - <0.10 kU/L
Cedar (Mountain)
Class 0 (Negative) - <0.10 kU/L
Cedar (Red)
Class 0 (Negative) - <0.10 kU/L
Oak (White)
Class 0 (Negative) - <0.10 kU/L
Elm (American)
Class 0 (Negative) - <0.10 kU/L
Ash (White)
Class 0 (Negative) - <0.10 kU/L
Hickory (White)
Class 0 (Negative) - <0.10 kU/L
Birch (Common Silver)
Class 0 (Negative) - <0.10 kU/L
Cottonwood
Class 0 (Negative) - <0.10 kU/L
Walnut
Class 0 (Negative) - <0.10 kU/L
White Mulberry
Class 0 (Negative) - <0.10 kU/L
Sweet Gum
Class 0 (Negative) - <0.10 kU/L
Maple/Box Elder
Class 0 (Negative) - <0.10 kU/L
Bayberry/Sweet Gale
Class 0 (Negative) - <0.10 kU/L

Weed Allergens

Ragweed
Class 0 (Negative) - <0.10 kU/L
Mugwort
Class 0 (Negative) - <0.10 kU/L
Lamb's Quarters
Class 0 (Negative) - <0.10 kU/L
Sagebrush
Class 0 (Negative) - <0.10 kU/L
Tumbleweed (Russian Thistle)
Class 0 (Negative) - <0.10 kU/L

Mold Allergens

Aspergillus fumigatus
Class 0 (Negative) - <0.10 kU/L
Candida albicans
Class 0 (Negative) - <0.10 kU/L
Cladosporium herbarum
Class 0 (Negative) - <0.10 kU/L
Penicillium notatum
Class 0 (Negative) - <0.10 kU/L

Food Allergens

Peanut
Class 0 (Negative) - <0.10 kU/L
Tree Nut (Almond)
Class 0 (Negative) - <0.10 kU/L
Tree Nut (Cashew)
Class 0 (Negative) - <0.10 kU/L
Tree Nut (Walnut)
Class 0 (Negative) - <0.10 kU/L
Milk (Cow)
Class 0 (Negative) - <0.10 kU/L
Egg (Chicken)
Class 0 (Negative) - <0.10 kU/L
Soy
Class 0 (Negative) - <0.10 kU/L
Wheat
Class 0 (Negative) - <0.10 kU/L
Sesame
Class 0 (Negative) - <0.10 kU/L
Shellfish (Shrimp)
Class 0 (Negative) - <0.10 kU/L
Shellfish (Crab)
Class 0 (Negative) - <0.10 kU/L
Fish
Class 0 (Negative) - <0.10 kU/L
Summary: Comprehensive allergen panel shows no detectable IgE antibodies to any tested allergens. Total IgE is low (9 IU/mL, normal <100). This indicates no allergic sensitization to common environmental, food, or inhalant allergens. Patient is not at risk for typical allergic reactions from these common sources.
Genetic Profile & Pharmacogenomics
Hemochromatosis Risk (HFE Gene - CRITICAL)
HFE C282Y Variant
Heterozygous Carrier (1 copy) ⚠️
HFE H63D Variant
Negative
Clinical Risk
Carrier status - Low to moderate risk. Requires iron monitoring.
MTHFR Status (Methylenetetrahydrofolate Reductase)
C677T Variant
Heterozygous (CT)
A1298C Variant
Heterozygous (AC)
Clinical Significance
Mild reduction in enzyme activity (~65% of normal)
Coagulation Testing (01/16/2026 & 02/24/2026) — Tested following Hemarthrosis

Factor V Leiden tested 01/16. Comprehensive coagulation factor panel and von Willebrand profile tested 02/24 to evaluate potential coagulopathy following joint bleeding.

Factor V Leiden (R506Q Mutation)
Negative (Normal/Normal) ✓
Factor VIII Activity (Coag Panel)
137% (ref 57-163) — Normal
Factor VIII Activity (vWF Panel)
147% (ref 56-140) — HIGH ⚠️
Factor IX Activity
91% (ref 60-177) — Normal
Factor XI Activity
90% (ref 60-150) — Normal
Fibrinogen Activity
226 mg/dL (ref 160-420) — Normal
APTT / PT / INR
28.2 sec / 10.8 sec / 1.0 — All Normal
D-Dimer Quantitative
0.37 ug/mL FEU (ref <0.50) — Normal ✓
von Willebrand Disease Assessment (02/24/2026)

Tested to evaluate for von Willebrand Disease as a cause of spontaneous hemarthrosis.

vWF Antigen
143% (ref 50-200) — Normal ✓
vWF Activity (Ristocetin Cofactor)
126% (ref 50-200) — Normal ✓
Factor VIII Activity
147% (ref 56-140) — HIGH ⚠️
Interpretation
Not consistent with von Willebrand Disease. Elevated Factor VIII is a recognized risk factor for venous thromboembolism (VTE).
Antiphospholipid Antibody Panel (01/16/2026 & 02/24/2026)

Comprehensive panel to rule out antiphospholipid syndrome (APS). Tested twice (01/16 & 02/24) — both negative, confirming no APS.

Cardiolipin Ab IgG
Negative ✓
Cardiolipin Ab IgM
Negative ✓
Cardiolipin Ab IgA
Negative ✓
Beta-2 Glycoprotein IgG
Negative ✓
Beta-2 Glycoprotein IgM
Negative ✓
Beta-2 Glycoprotein IgA
Negative ✓
Panel Interpretation
All antiphospholipid antibodies negative on two separate occasions (01/16 & 02/24/2026). Definitively rules out antiphospholipid syndrome.
Cardiovascular Risk (Thrombosis & Hemostasis)
Factor V Leiden
Negative (confirmed 01/16/2026)
Factor II Prothrombin G20210A
Negative
PAI-1 (Plasminogen Activator Inhibitor-1)
4G/5G Heterozygous
Factor VIII Activity (02/24/2026)
147% (ref 56-140) — Elevated. Independent risk factor for VTE ⚠️
Risk Assessment
No inherited thrombophilia (Factor V Leiden negative, Prothrombin G20210A negative). Elevated Factor VIII noted — monitor and consider hematology evaluation if thrombotic event occurs.
Pharmacogenomics (Drug Metabolism)
CYP3A4 (Major Drug Metabolizer)
Normal Metabolizer (*1/*1)
CYP2D6 (Antidepressant/Opioid Metabolism)
Normal Metabolizer (*1/*1)
CYP2C19 (SSRI/Warfarin Metabolism)
Intermediate Metabolizer (*1/*2)
TPMT (Thiopurine Metabolism)
Normal Activity
ALDH2 (Alcohol Metabolism)
Normal Metabolizer
Other Notable Genetic Markers
ApoE (Apolipoprotein E)
ε3/ε3 (Normal lipid metabolism)
ACE (Angiotensin-Converting Enzyme)
II Genotype (Associated with better cardiovascular fitness)
Lactase Persistence
CC Genotype (Lactose tolerant)
CETP (Cholesterol Ester Transfer Protein)
TaqIB: BB Genotype (Associated with protective HDL levels)
Summary: Genetic profile shows generally favorable markers with normal drug metabolism for most medications. MTHFR heterozygous status (both variants) suggests mild reduction in methylation capacity but not clinically significant. Coagulation workup (01/16 & 02/24/2026): Factor V Leiden negative, full Antiphospholipid panel negative on two occasions, von Willebrand Disease ruled out (vWF Antigen 143%, Activity 126% — both normal). Comprehensive coagulation factors (VIII, IX, XI, Fibrinogen, APTT, PT, INR, D-Dimer) all normal. Notable finding: Factor VIII Activity elevated at 147% (ref 56-140) on vWF panel — recognized independent risk factor for venous thromboembolism. Uric acid normal (5.6 mg/dL), ruling out gout. Lipid metabolism markers (ApoE ε3/ε3, ACE II, CETP BB) are associated with better cardiovascular health outcomes. CYP2C19 intermediate metabolizer status may warrant dose adjustments for certain SSRIs or warfarin if prescribed.
Data Archive & Historical Records

Complete list of all tests performed from 2017-2026, organized by date.

Test Date Test Type Number of Tests Key Results Status
12/18/2017 CBC, CMP, Lipids 26 tests All normal; baseline established Normal
08/28/2018 CBC, CMP, Liver, Allergen IgE 32 tests Bilirubin elevated (1.5); B12 elevated (1728); allergies negative ALERT
02/07/2020 Renal Panel, Electrolytes, UA 18 tests Kidney function normal; bilirubin normalized Normal
04/27/2023 Allergen-Specific IgE (Focused) 12 tests All allergens negative; low total IgE Normal
11/18/2024 Rheumatology Panel, CBC, Immune 48 tests AST, ALT significantly elevated (62, 95); all autoimmune negative HIGH ALERT
07/17/2025 CBC, CMP, Lipids 28 tests Liver enzymes normalized; all values improved Normal
01/04/2026 Synovial Fluid Analysis (Right Elbow) 5 tests Hemarthrosis detected; RBC 3.2M, elevated neutrophils CRITICAL
01/12/2026 C1 Esterase, Tryptase, Complement 3 tests All within normal limits; no angioedema or mast cell disorder Normal
01/16/2026 CBC, CMP, Liver, Coag, UA, C1/Tryptase 52 tests All normal; LDH 232 (slight high), urine pH 8.0 (high). Factor V Leiden & APS negative. Normal
01/19/2026 LDH Isoenzymes (LD Fractions) 6 tests LDH Total elevated (231); all fractions normal distribution MONITOR
02/24/2026 Coagulation, vWF Profile, APS, Uric Acid 18 tests Factor VIII elevated (147%); vWD & APS ruled out; uric acid normal (5.6); coag factors normal FVIII HIGH
Archive Summary: Medical records spanning 9 years (2017-2026) show overall good health trajectory. Key findings in January 2026: hemarthrosis (bleeding in right elbow joint) detected via synovial fluid analysis on 01/04/2026. Extensive follow-up testing completed 01/16/2026: Factor V Leiden negative, Antiphospholipid panel negative, C1 Esterase Inhibitor (serum & functional) normal, Tryptase normal. CBC and CMP all within normal limits with excellent kidney function (eGFR 105). Inflammatory markers (ESR 2, CRP <1) show no systemic inflammation. Liver enzymes fully normalized (AST 26, ALT 25). LDH slightly elevated at 232 but isoenzymes show normal distribution. February 2026 workup (02/24): Comprehensive coagulation factor panel (VIII, IX, XI, Fibrinogen, APTT, PT, INR, D-Dimer) all normal. Von Willebrand Disease assessment: vWF Antigen 143% and Activity 126% — both normal, ruling out vWD. Antiphospholipid antibodies repeated — all negative (second confirmation). Uric acid 5.6 mg/dL — normal, ruling out gout. Notable: Factor VIII Activity elevated at 147% (ref 56-140), a recognized VTE risk factor. Current status: Hemarthrosis cause remains undetermined; no inherited coagulopathy, vWD, APS, or crystal arthropathy identified. Elevated Factor VIII requires monitoring.