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Ordered Items: LDH Isoenzymes (LD Fractionation)
Clinical Indication: Follow-up to elevated LDH Total (232 IU/L on 01/16/2026) to identify tissue source
LDH Total
| Test |
Result |
Flag |
Previous Result |
Units |
Reference Interval |
| LDH Total |
231 |
HIGH |
232 (01/16/2026) |
IU/L |
121-224 |
LD Isoenzyme Fractions
LDH exists as 5 isoenzymes (LD1-LD5) in different tissues. Fractionation helps identify which tissues may be damaged when total LDH is elevated.
LD Fraction 1
31%
Heart, RBC
Ref: 17-32%
LD Fraction 2
34%
Heart, RBC
Ref: 25-40%
LD Fraction 3
20%
Lung, Lymph
Ref: 17-27%
LD Fraction 4
8%
Liver, Muscle
Ref: 5-13%
LD Fraction 5
7%
Liver, Muscle
Ref: 4-20%
| Fraction |
Result |
Status |
Reference Interval |
Primary Tissue Source |
| LD Fraction 1 |
31% |
Normal |
17-32% |
Heart, Red Blood Cells |
| LD Fraction 2 |
34% |
Normal |
25-40% |
Heart, Red Blood Cells |
| LD Fraction 3 |
20% |
Normal |
17-27% |
Lung, Lymphocytes, Pancreas |
| LD Fraction 4 |
8% |
Normal |
5-13% |
Liver, Skeletal Muscle |
| LD Fraction 5 |
7% |
Normal |
4-20% |
Liver, Skeletal Muscle |
Clinical Interpretation:
While total LDH is slightly elevated at 231 IU/L (compared to 232 on 01/16/2026),
all individual LD fractions are within normal limits.
Key findings:
- LD1/LD2 Ratio Normal: The normal LD1/LD2 ratio rules out acute myocardial infarction (where LD1 > LD2, called "flipped ratio") and significant hemolysis.
- LD4/LD5 Normal: Normal LD4 and LD5 suggest no active liver or skeletal muscle damage.
- LD3 Normal: Rules out significant lung or lymphatic involvement.
Conclusion: The mild LDH elevation may be due to minor cellular turnover, sample handling, or benign variation. No evidence of acute tissue damage to heart, liver, muscle, or lungs. Continue monitoring; no urgent intervention needed.
Patient Details
Bishop, Tyler
3434 VOYAGER CIR, SAN DIEGO, CA, 92130
Phone: 636-448-1747
DOB: 05/26/1987 | Age: 38 | Sex: Male
Physician Details
Ordering Physician
San Diego, CA
Specimen Details
Date Collected: 01/19/2026
Date Reported: 01/20/2026
Performing Lab: Labcorp
For inquiries: 800-859-6046 | Lab: 858-668-3700